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2124 In early postpartum, there is an additional mechanism that may also contribute towards creating greater oxidative stress, since, during days 46 postpartum, after the 100- to 500-fold drop in estrogen levels, there is, approximately, a 40% elevation in monoamine oxidase-A (MAO-A) levels throughout all grey matter brain regions, including those that regulate affect, such as the prefrontal cortex and anterior cingulate cortex, 25 MAO-A creates hydrogen peroxide when it catalyses the deamination of serotonin, dopamine, and norepinephrine

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However, what is normal can vary from person to person