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Weight regain after discontinuation is well documented, with studies showing that most patients regain 50 to 70 percent of lost weight within 12 months of stopping treatment

In fact, research published in the journal Nutrients confirms that several vitamins and co-factors play key roles in neuroprotection, nerve conduction, and inflammation control (source)

Alterations in anxiety-like behavior following knockout of the uncoupling protein 2 (ucp2) gene in mice