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In that respect, low-fructose diets, FKS1 inhibition, and the greater entrance to aerobic metabolic pathways are possible therapies to evaluate in the cirrhotic population (Table 1)

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Key outcomes from the 84-week study: Mean weight loss: CagriSema 23% Tirzepatide 25.5% Treatment-regimen estimand (all randomized patients): CagriSema 20.2% Tirzepatide 23.6% While CagriSema demonstrated clinically meaningful weight reduction, it fell short of the predefined statistical threshold for non-inferiority