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Tirzepatide is a dual GIP/GLP-1 receptor agonist, meaning it targets two incretin pathways instead of just one

The STEP 8 clinical trials found that once-weekly semaglutide 2.4 mg led to significantly greater weight loss than once-daily liraglutide 3.0 mg at 68 weeks in overweight adults without diabetes

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Competing Interests The authors declare that they have no competing interests Materials and Methods Plasmid construction Amino acids mutations to switch Rex-domain specificity from NAD to NADP were selected based on a previous screen [15]