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Unexplained hypercobalaminemia, particularly levels above 1,000 pg/mL, has been associated with liver disease, kidney dysfunction, myeloproliferative disorders, and certain solid cancers in multiple large-scale studies

therefore, pan-coronavirus vaccines would need to target epitopes that can inhibit binding to all coronavirus entry receptors

For example, people who follow vegetarian or vegan diets may have a higher risk of B12 deficiency because the vitamin is not naturally present in plant-based foods

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