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Many women report reduced anxiety and improved mood after starting treatment, partly from the weight loss itself and partly from the direct neurological effects of GLP-1 receptor activation on mood-regulating brain circuits

April 2025, Northstrive Biosciences In semaglutide to reduce the risk of serious heart problems in obese or overweight adults, and semaglutide becomes the first we igh58 t loss drug approved in the UK as a preventative treatment for those with established cardiovascular disease

It signals the brain to feel full faster, reducing hunger

But in appropriate cases, it can reduce medication burden and support long-term balance without rebound weight gain