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PLB treatment significantly decreased iron ions and LPO, suggesting its role in ferroptosis inhibition, but YTHDF1 overexpression reversed these effects (Fig
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(Source 2, 3) "The primary downside of iron supplementation is the high rate of potential side effects, particularly gastrointestinal side effects, including nausea, vomiting, and constipation." Potential Side Effects of Iron Iron supplements, especially when taken without food on an empty stomach, can sometimes cause side effects such as constipation, nausea, stomach cramps, or a metallic taste-especially with traditional forms like ferrous sulfate