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The medication can be kept at room temperature for short periods when preparing an injection, but prolonged exposure to room temperature should be avoided unless specified by the pharmacy

Injection site monitoring prevents local complications

A patients medical history, glucose metabolism, medications, and other clinical factors may need to be considered

Controlled freezing studies of recombinant hGH demonstrated that insoluble particulate aggregation increases sharply with cooling rate, with pH 7.4 formulations producing markedly more light-scattering particulates than pH 7.8 formulations after freeze-thaw (Eckhardt, Oeswein & Bewley, 1991)