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A proposed concept for defective mitophagy leading to late stage ineffective erythropoiesis in pyruvate kinase deficiency

Thus, we exemplified with BPC 157 therapy many targetsmuscular, vascular, nerve, peripheral, and centralthat share functions with the multimodal muscle axis [12,13]

Relapse during the double-blind phase was defined as having 2 or more binge days each week for two consecutive weeks (14 days) prior to any visit and having an increase in CGI-S score of 2 or more points compared to the randomized-withdrawal baseline