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In these participants, concentrations of latent myostatin, a pharmacodynamic marker, increased substantially after the first dose, achieved a plateau at approximately week 16 and remained consistently elevated throughout the treatment period, demonstrating successful target engagement (Extended Data Fig

Dosing errors are unlikely to cause serious harm

That confusion is common because semaglutide began as a diabetes drug before becoming widely known for weight management

Eating smaller meals, keeping fat moderate, increasing fiber, and staying hydrated can help reduce nausea, reflux, and other digestive side effects