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Hypothesizing that the compounds suppress metabolism and therefore block viral gene expression, adding the inhibitors 2 h after infection, when entry has occurred, should not have a dramatic negative impact on their antiviral activity

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According to the data derived from the SBVS, the interaction between DPDPE and GLP1R was characterized by a similar localization than danuglipron and orforglipron, within the TM bundle, and more concretely, closer to TM1-2 region (Figure 4)