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This modification significantly improves oral bioavailability and stability without changing the peptide biological activity once it reaches target tissues

Research suggests that GLP-1 and GIP medications work best when they are part of a comprehensive lifestyle change

Many people regain weight when they stop taking them, which is why patients should think carefully about whether they are ready for long-term treatment, at least until we have better evidence on how to maintain weight loss after stopping medication or treatments that more durably change the course of obesity