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Figure 1 2 Biology of ApoE 2.1 Structure Human ApoE is a ~ 34 kDa glycoprotein composed of 299 amino acids and is part of the family of amphiphilic exchangeable lipoproteins (Mahley, 1988)

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It does: - Reduce cravings - Block alcohol's reward - Lower heavy drinking days It doesn't: - Cure addiction instantly - Fix the underlying habits and triggers - Replace therapy, support, or lifestyle change Success requires consistent dosing, patience with the process, and some lifestyle adjustments

The other 5.9 million Part D enrollees met the clinical criteria but also had claims or encounter data recording a diagnosis of type 2 diabetes, OSA, or MASH, and/or had a GLP-1 Part D-covered prescription, either of which would make them ineligible for Bridge