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Phase 2 data published in the New England Journal of Medicine (2023) reported mean body weight reductions of up to 24.2% at the highest dose cohort over 48 weeks, surpassing outcomes seen with dual or single-receptor agents in equivalent trials

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Use proper needle technique by pinching the skin, inserting the needle at a 90 angle (or 45 if your skin is very thin), and choosing smaller-gauge needles for less discomfort