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Psychiatry 20 , 4151 (2016)

The gene deleted in a mutant was marked with a number in the name of the constructed strain (Table 1)

In human skin fibroblasts, Nrf2-driven antioxidant enzyme expression translated into: Reduced intracellular ROS Improved mitochondrial membrane potential Protection against senescence-associated cell damage [36] In human gingival and periodontal stem cells, Epitalon significantly reduced aging biomarkers such as p16 and p21, decreased ROS levels, and preserved mitochondrial function, even under stress [42]

The available data are sufficient to show that iron accumulation is more obvious in the pancreas, liver, and heart, all of which are traditional tissues with excessive iron