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By increasing thermogenesis, it stimulates the production of heat in the body, which, in turn, can boost calorie burning and fat loss

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Biomarker-Informed Assessment Before Adjusting Treatment Before increasing tirzepatide dose, a qualified provider should evaluate relevant biomarkers to rule out underlying metabolic or endocrine factors

However, long-term use of vitamin E may increase the risk of prostate cancer and hemorrhagic shock, so vitamin E should not be used for long-term treatment of MASH and MASLD (259)