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16 hours before the last dose, food was removed, and 1 hour after the last dose, the mice received an intraperitoneal dose of recombinant leptin (LY355101) or vehicle

GHRP-2 stimulates growth hormone release, which promotes lipolysis (fat breakdown) However, GHRP-2 increases food intake by 35.9% in healthy individuals The appetite increase is dose-dependent (10-34% increase depending on dose) Fat loss requires strict dietary control to counteract increased hunger GHRP-2 works best as part of a comprehensive body recomposition strategy , not as a standalone fat loss agent Effects are similar in both lean and obese individuals The research is clear: GHRP-2, like its natural counterpart ghrelin, acts as a potent appetite stimulant

doi: 10.1016/j.freeradbiomed.2022.10.270 33 LiuD.LiangC