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The intralesionally given, CMP-001 is undergoing clinical trials as monotherapies and in various combinations with systemic immunotherapies
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doi: 10.1016/j.clinthera.2019.02.011 489 Carlo-StellaNBozziniSDe SilvestriASbarsiIPizzocheroCLorussoLet al
Because CJC-1295 acts upstream of growth hormone, its safety profile is tied to two overlapping issues: Peptide-specific effects , such as injection-site reactions or transient flushing GH/IGF-1-axis effects , such as fluid retention, joint discomfort, changes in glucose handling, or other effects associated with elevated growth hormone signaling The safety discussion is also complicated by naming
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