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In musculatura striata (cea scheletica, responsabila de miscarea organismului) si in muschiul cardiac, o contributie majora la productia de energie o are oxidarea acizilor grasi

The findings with DPP-4 inhibitors also differ from the responses reported with SGLT2 inhibitors, which (in two trials) were reported to reduce major adverse cardiovascular events, especially the risk of new-onset heart failure [55, 56]

These receptors are highly concentrated in adipose tissue (particularly visceral fat and brown fat) but have limited expression in most other tissues in adult humans

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