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It is possible that, in addition to factors such as reduced alcohol consumption, weight loss-related improvements in body image, or relief associated with better glycemic control in diabetes, there may also be direct neurobiological mechanisms involved -- for example, through changes in the functioning of the brain's reward system," said Research Director, Docent Markku Lhteenvuo from the University of Eastern Finland

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Inflammation and Gut-Brain Axis Link Obesity to Cognitive Dysfunction: Plausible Pharmacological Interventions

NAD is a coenzyme involved in cellular energy production across many pathways