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The kit uses a proprietary non-fluorescent dye that becomes strongly fluorescent upon reacting with thiol

Basal-like breast cancer, characterized by its more aggressive clinical behavior compared to the luminal subtype, exhibits elevated levels of the miRNAs including miR-221 and miR-222

Notable features of such click reactions include high yields, lack of side products, compatibility with aqueous conditions and orthogonality to many other synthetic reactions

The pannus invades the periarticular bone at the cartilage-bone junction and leads to the progressive destruction of cartilage and subchondral bone tissue [69]