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*Correspondence: Lei Xu, [email protected] Liu, [email protected] These authors have contributed equally to this work This article was submitted to Cellular Neuropathology, a section of the journal Frontiers in Cellular Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Product Specifications Peptide: IGF-1 LR3 Type: Synthetic IGF-1 analog Amino Acids: 83 Molecular Formula: CHNOS Molecular Weight: ~9,111 g/mol CAS Number: 946870-92-4 Purity: 99% (HPLC Verified) Form: Lyophilized powder Quality & Compliance HPLC & MS verified Manufactured under controlled conditions For Research Use Only (RUO) Not for human or veterinary use This product is intended strictly for research purposes only and is not approved for human or veterinary use .

If it refers to a diet deficiency, select D50.1

9 During pathological states, reaction between nitric oxide and superoxide can generate highly reactive peroxynitrite (ONOO-) radicals, which are implicated in lipid peroxidation