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Biomarker-Guided Stratification as a Future tool NET-related biomarkersincluding citrullinated histone H3, MPODNA complexes, and cell-free dsDNAcould help identify high-NET phenotypes and inform therapy selection, though standardization and prospective clinical studies are still needed

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Big Pharma is still piling in: Pfizer closed its 2023 $43B Seagen deal to expand its ADC platform, and PD-1 biosimilars are expected to arrive late-decade, expanding access rather than collapsing the category, as CRA Insights noted

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