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5-Amino-1MQ (5-Amino-1-methylquinolinium iodide, CAS 42464-96-0) is a synthetic small-molecule quaternary quinolinium compound that functions as a selective substrate site-targeting inhibitor of nicotinamide N-methyltransferase (NNMT)

16: One of the most-anticipated FDA decisions of the first half of 2024 came early as the regulator approved Vertex Pharmaceuticals and CRISPR Therapeutics Casgevy (exagamglogene autotemcel) as a one-time treatment for transfusion-dependent beta-thalassemia (TDT)

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