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IGF-1 LR3 administered during this window produces 23 the protein synthesis response compared to administration at rest

To assess whether RT probe binds to any proteins or reacts with free cysteine residues in some proteins that may interfere with the final ratio readouts, we incubated RT with cell lysate, which was dialyzed using a 3 K cut-off membrane to remove all small molecules including GSH, and observed no significant changes in fluorescent signal ratios even at the highest lysate concentration shown (protein concentration is 36 mg ml 1 based on a BCA assay), suggesting that there is no non-specific interactions or reactions between cellular proteins and RT which could significantly change the ratio readouts (Fig

Faster-appearing changes often reflect superficial effects rather than the deep structural improvements copper peptides provide

This difference in selectivity means that while both can boost GH, Ipamorelin is often considered to have a cleaner profile in terms of potential side effects