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Protocol compliance: Consistent dosing and proper storage maximize results
Several studies have investigated potential therapeutic interventions to mitigate cyclosporin-induced hepatotoxicity
Suppression of the murine osteoblasts MC3T3-E1 proliferation by dexamethasone (Dex) was associated with G1 phase delay and apoptosis induction accompanied by p53-dependent activation of p21 and the up-regulation of proapoptotic genes NOXA and PUMA [24]
Short-acting agents may have more persistent meal-to-meal gastric-emptying effects, while long-acting agents may show attenuation of this effect over time
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