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It acts like a control centre, sending signals that tell the vessels when to widen (dilate) or narrow (constrict)

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However, when measurable tumors appeared in BPT mice around 5 weeks, Epac1/2 double heterozygous ( Epac1 +/ /Epac2 +/ ) and double homozygous ( Epac1 / /Epac2 / ) mice had significantly smaller or no palpable tumors (Figs