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The groups that received the riboflavin-fortified salt had lower rates of esophageal cancer.[ref] Inflammatory Bowel Disease (IBD): In patients with Crohns disease, riboflavin (100mg/day) decreased inflammatory markers significantly in three weeks.[ref] Related article: IBD and Genetic Connections Inflammation: A randomized, placebo-controlled trial of supplemental riboflavin found that it reduced inflammation based on a lower CRP level.[ref] Related article : Inflammation and chronic disease Gut microbiome interactions with riboflavin: Certain gut microbes can produce riboflavin, part of which is then absorbed into the body

Vitamin B12 is an essential component of a number of enzymes which are involved in normal metabolism

These observations identify SIM1 stimulation as a potential antiobesity strategy