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We reasoned that GLP-1(7-36) and (9-36) may still inhibit glucagon secretion in Gcgr / islets by activation of GLP-1Rs in - or -cells

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For example, if the glutaredoxin sulfur atom in Grx(SSR) species was accessible for a productive reaction with GSH, one would not expect to trap such species by monothiol glutaredoxin mutants 83,84,85

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