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The earlier published trial findings from ASPREE in 2018 showed aspirin did not prolong healthy independent living but was associated with a significantly increased risk of bleeding, primarily in the gastrointestinal tract, Dr

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However, urine output is not a very reliable index in patients who are taking medication or are perioperative, and other commonly used surrogate indices, such as the serum creatinine concentration, creatinine clearance, or GFR, can only show that AKI and functional impairment is already present, rather than being predictors of their development at an early stage (113)