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doi: 10.3389/fphar.2025.1539886 Received 05 December 2024 Accepted 20 January 2025 Published 19 February 2025 Volume 16 - 2025 Edited by Abeda Jamadar, University of Kansas Medical Center, United States Reviewed by Aabid Hussain, Cleveland Clinic, United States Venkata Sanaboyana, Corteva Agriscience, United States Ashish Dhayani, University of Pittsburgh, United States Afsana Naaz, University of Pittsburgh, United States Updates Copyright 2025 Chen, Deng, Hu and Gong

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This loss of balance is critical in epilepsy because GABAergic inputs help regulate synaptic plasticitythe way neurons adapt to changesat nearby glutamatergic synapses