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Table 1 summarizes subtypes of hemochromatosis, genes involved, and clinical manifestations Overall reduced hepcidin levels result in the upregulation of ferroportin expression on enterocytes, hepatocytes, and macrophages, leading to increased iron efflux into circulation

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30 Type II and IV hypersensitivities may be involved in the pathogenesis of chronic disease from bradyzoites in tissue cysts

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