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"The majority of the reports described patients mistakenly drawing up more than the prescribed dose from a multiple-dose vial during self-administration," officials at the FDA explain

To confirm that tree-based ML models are the most appropriate for our analysis we also built Least Absolute Shrinkage and Selection Operator (LASSO) models to predict circulating TMAO in the left-out group using again fivefold cross-validation with all the available variables (full model) as input in BMIS ( N = 582