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Zinman B, Wanner C, Lachin JM, Fitchett D, Bluhmki E, Hantel S, Mattheus M, Devins T, Johansen OE, Woerle HJ, Broedl UC, Inzucchi SE

The authors explicitly stated that the study was "not intended to provide guidance on the sublingual dosing of semaglutide in humans." Extrapolating from a rat study on a different peptide to human use of tirzepatide drops involves multiple leaps of scientific faith that responsible review cannot endorse

It is advisable to avoid layering multiple copper-containing products within the same regimen, as cumulative exposure may elevate copper levels beyond what is considered safe for topical use

It represents a middle ground between localized fat dissolvers and systemic weight loss compounds