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Therefore, while HO-1 exerts cytoprotective effects under stress, its upregulation may paradoxically exacerbate iron-dependent cell injury when downstream iron-handling pathways are overwhelmed or dysfunctional

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Higher Dosages : In some treatment protocols, larger doses of B12 may be required, ranging from 1 ml to 3 ml

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Food and Drug Administration (FDA) in 1996 for treating epilepsy and preventing seizures, later found application in migraine prevention

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85 (4) e00104-21: e0010421

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