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Mechanistically, statins altered the bile-acid pool (notably lowering ursodeoxycholic acid, UDCA), which reduced signaling through the TGR5 receptor on intestinal cells, leading to less GLP-1 release

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However, due to possible GI issues that affect absorption, its important to review all medications with your provider

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on the other hand, changes of gut microbial composition during neurodevelopment in early life may be detrimental for the CNS and leads to neurological disorders in later life (Louwies et al., 2019)

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