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If it helps manage and prevent those life-threatening risks, then for that patient it is probably better to continue it. The TGA said it first became aware of the link to NAION in 2024 after a study published in a peer-reviewed medical journal raised concerns, and further evidence of the potential links has since been closely monitored

The absence of a patient information leaflet, dosing guidance, or medical supervision makes self-administration of bulk-sourced retatrutide inherently unsafe

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They can have risky side effects Some of the more common side effects of GLP-1 drugs include nausea, vomiting, and diarrhea, but there also have been reports of issues such as sagging and wrinkling of skin