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Retatrutide dosage In phase 2 clinical trials, retatrutide was given in the following doses: 1mg, 2mg or 4mg (starting dose) 1mg, 4mg, 8mg or 12mg per week (maintenance dose) 12mg per week (maximum dose) The dose escalation was similar to other weight loss medications, with the retatrutide dose increasing every 4 weeks

Many people microdosing GLP-1 medications are taking a compounded GLP-1, which means the drug was made in a compounded pharmacy and not approved by the FDA for safety, quality or efficiency

In a separate trial involving patients with type 2 diabetes, Retatrutide reduced A1C levels, which measure blood sugar, by up to 2 percentage points and produced an average weight loss of 16.8% after 40 weeks

however, Virginia Medicaid provides quarterly reports on its total GLP-1 spending