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The most common side effects reported in SURPASS 1 trial (as compared with placebo) were abdominal discomfort, nausea, diarrhoea (1218%), injection site reactions (23%), and hypersensitivity (12%)
Tirzepatide plus either cyanocobalamin or methylcobalamin, in bacteriostatic water, at a concentration typically ranging from 2 mg/mL to 10 mg/mL
Participants were advised to abstain from taking vitamin D, testosterone supplements, or steroid- containing over the counter or prescribed medications for 30 days before the study period
Limitations of Animal Studies One limitation of relying on animal studies is that animals and humans do not always react to medications in the same way
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