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Identification of arogenate-specific TyrA among many non-photosynthetic microbes may require revisiting the biological significance of the ADH vs

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thermophilus ) are observed to induce mucosal IgA production by SCFAs such as butyrate, which inhibit HDACs to epigenetically activate TGF-/Smad3 signaling in DCs, resulting in class-switching of B cells to IgA+ plasma cells in the gut mucosal lining in a dose-dependent manner (143, 144)

Again, evidence is primarily animal-based, not FDA approved