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Clinical dilemmas of MDR in refractory tumors The clinical management of MDR in refractory cancersincluding pancreatic cancer, glioblastoma, triple-negative breast cancer (TNBC), and platinum-resistant ovarian cancer (see Table 1)remains a formidable and largely unmet challenge, as both conventional and emerging therapeutic strategies frequently encounter failure

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Ozempic is the brand name for semaglutide, a prescription medication approved by the FDA for treating type 2 diabetes