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Liposuction, specifically tumescent technique or water-assisted liposuction, represents the only treatment that directly removes lipedema fat, but it is invasive, costly, often requires multiple staged procedures, and is not universally accessible

[DOI] [PMC free article] [PubMed] [Google Scholar] 70.de Oliveira H.A., Antonio E.L., Arsa G., Santana E.T., Silva F.A., Jnior D.A., Dos Santos S., de Carvalho P.T.C., Leal-Junior E.C.P., Araujo A., et al

Because of these variables, IGF-1 LR3 dosage protocols should be individualized rather than copied from online forums