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WernickeKorsakoff syndrome Wernicke encephalopathy (acute) Confusion Ataxia Ophthalmoplegia / nystagmus Korsakoff psychosis (chronic) Memory loss Confabulation Learning difficulties Diagnosis Mainly clinical Erythrocyte transketolase activity Response to thiamine supplementation MRI brain (Wernicke): mammillary body changes Management Thiamine replacement IV thiamine in severe cases Oral thiamine for maintenance Always give thiamine before glucose Prevents worsening lactic acidosis and Wernicke encephalopathy Treat underlying cause (nutrition, alcohol use) Prevention Balanced diet Thiamine supplementation in high-risk patients Fortified foods Alcoholic + confusion + ataxia + eye signs Wernicke Heart failure with malnutrition Wet beriberi Neuropathy without edema Dry beriberi Glucose before thiamine is dangerous To view or add a comment, sign in 39,658 followers

Prescription medicines can produce larger average losses but they are injectable options and come with their own risks and monitoring requirements

Glutathione works as a powerful antioxidant by neutralizing free radicals and reducing oxidative stress, which helps protect cells from damage

The Medicines and Healthcare products Regulatory Agency (MHRA) has revised the product information of semaglutide on Thursday (5), indicating a rare risk of vision loss