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92 In the subgroup analysis by preserved versus reduced LVEF, there was no difference between treatment and placebo

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Most patients increase their dose every four weeks, moving from 2.5mg through 5mg, 7.5mg, 10mg, and potentially up to 15mg depending on response and tolerance

Instead of continuing full therapeutic doses, the goal of maintenance is to: Keep appetite and cravings stable Support metabolic balance Prevent rapid rebound weight gain Allow your body to adjust gradually Why GLP-1 Maintenance Matters GLP-1 medications work at multiple levels: blood sugar regulation, appetite signaling, digestion speed, insulin release, and even reward-based eating patterns