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Even in the presence of only 1 M O 2 representative of hypoxia or oxygen-deprived areas of the liver under homeostatic conditionsthe interaction of NFT with O 2 is still 200-fold faster than its interaction with GSH (Miller et al

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Consider oxidative stress markers (8-OHdG, MDA), direct glutathione measurement (GSH:GSSG ratio), mitochondrial function indicators, inflammatory markers (hs-CRP, IL-6), and genetic assessment of detoxification capacity