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Within the same period, the dispensed prescriptions within the benefit to incident patients with a preexisting diagnosis of obesity without T2DM increased by 270% (4.0 to 14.6%), and 502% for patients with neither obesity nor T2DM (5.3 to 32.1%), and 515% for patients without any of the included diagnoses (4.2 to 25.7%) (see Table 9 in the Appendix)

Further basic and translational research is needed to identify individuals more susceptible to ROS damage, and to clarify whether ROS is an important target to treat COPD and AATD patients

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