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The exogenous pathway involves the digestion and absorption starting from dietary fats, while the endogenous pathway manages the liver's production and distribution of fats within the body which involves the group of lipoprotein which is very low-density lipoprotein (VLDL) primarily responsible for transporting triglycerides (the most common type of fat in the body) from the liver to various tissues

After the incubation, the samples were run on 6% native polyacrylamide gel containing 0.5Tris-borate-EDTA buffer

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Semaglutide significantly reduced this reinstatement of drug-seeking behavior at the higher doses