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Front Neurosci 14:229 Gong B, Pan Y, Vempati P, Zhao W, Knable L, Ho L, Wang J, Sastre M, Ono K, Sauve AA, Pasinetti GM (2013) Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-gamma coactivator 1alpha regulated beta-secretase 1 degradation and mitochondrial gene expression in Alzheimers mouse models

PMID 27059958

Daily dosing vs three times weekly dosing The question of whether you can reduce from daily to three times per week comes up frequently with sublingual GLP-1 drops

Along with convenience, affordability and safety, another important factor is bioavailability