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In addition to reducing CoQ, GTP cyclohydrolase-1 (GCH1) could produce tetrahydrobiopterin/dihydrobiopterin (BH4/BH2), thereby antagonizing ferroptosis independent of GPX4 by inhibiting lipid peroxidation [71]

Breast 66:6976 Sousa-Pimenta M, Estevinho LM, Szopa A, Basit M, Khan K, Armaghan M et al (2023) Chemotherapeutic properties and side-effects associated with the clinical practice of terpene alkaloids: paclitaxel, docetaxel, and Cabazitaxel