MiR-25 is overexpressed in both keratinocytes and melanocytes in response to oxidative stress, which decreases the activity of antioxidant enzymes and impairs melanosome transport, leading to redox imbalance [51]
[DOI] [PubMed] [Google Scholar] 51.Baumgardner J.N., Shankar K., Hennings L., Albano E., Badger T.M., Ronis M.J
Urolithin A Urolithin A is a postbiotic, a byproduct of probiotic bacteria active in your gut.85 This particular postbiotic has garnered a lot of attention for its ability to induce mitophagy, the removal of dead or damaged mitochondria from cells.86 Mitophagy prevents these unwanted mitochondria from hanging around, building up, and causing various aging-related diseases and disorders.87 Brain aging and mood Heart disease remains the number one killer in the U.S., with Alzheimers disease occupying a spot on the list just a few items down.79 The former correlates directly with stress, while the latter has a known relationship with stress thats still under investigation.18 19 As increasing longevity remains a key component of any anti-aging regimen, mitigating stress and attending to your mood seems central to the effort
By understanding the distinct roles of these two powerhouse molecules, you can build a routine that feels tailored to your life
